The termite collection is located on the ground floor, Building 005, BARC-West, Beltsville, MD. The associated library includes about 100 volumes and 60 linear feet of reprints. The collection consists of 240,000 specimens, with examples of 1,286 species, and includes 943 types. The SEL scientist that works with the Isoptera collection is David. A. Nickle.

The Isoptera collection is one of the largest in the world, primarily through the efforts of T. E. Snyder (USDA), with extensive additions recently made by D. A. Nickle and M. S. Collins. The collection has worldwide representation and is especially rich in species from the West Indies, Central America, and the Amazon Basin.